Cancer Res Treat.  2009 Dec;41(4):241-244.

A Case of Spine Origin Chondroblastoma Metastasis to Lung

• Sohn SH
• Koh SA
• Kim DG
• Park SW
• Lee KH
• Kim MK
• Choi JH
• Hyun MS

Abstract

Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur. Chondroblastoma can affect people of all ages. It is, however, most common in children and young adults between the ages of 10 and 20 years. Although most chondroblastomas are cured by limited surgical procedures, occasional lesions behave more aggressively and may even metastasis. In this case a young man with pulmonary metastatic chondroblastoma on spine is presented. Unlike previously published examples of metastatic chondroblastoma, these metastasis developed before any operative manipulation of the primary tumor. And primary tumor site was also unusual. The histologic characteristics of the primary, metastatic tumors were those of a conventional chondroblastoma.

Keyword

Chondroblastoma; Spine origin; Lung metastasis

MeSH Terms

Child
Chondroblastoma
Epiphyses
Femur
Humans
Humerus
Lung
Neoplasm Metastasis
Spine
Tibia
Young Adult

Figure

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  Fig. 1 L-spine MRI shows low-intensity signal on T I (A) and high-intensity signal on T II weighted images (B).

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  Fig. 2 L-spine AP (B), rateral (A). X-ray shows osteolytic lesion on L4.

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  Fig. 3 L-spine CT shows Low density mass like lesion.

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  Fig. 4 Histopathological findings tissue from L-spine CT guided bone Biopsy. Round to poly gonal cells, round to ovoid nuclei, osteoclastic giant cells (H&E staining, ×40).

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  Fig. 5 PET-CT shows metastatic lung nodules.

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