Korean J Asthma Allergy Clin Immunol.  2012 Jun;32(2):131-135.

Two Cases of Acute Generalized Exanthematous Pustulosis Induced by Ingestion of Lacquer Chicken

Abstract

BACKGROUND
Acute generalized exanthematous pustulosis (AGEP) is a rare severe pustular cutaneous eruption associated with fever and leukocytosis. Rarely, intake of lacquer chicken can induce AGEP. CASE HISTORY: We described two cases of AGEP developed after ingestion of lacquer chicken, which showed a positive patch test and were accompanied by unusual clinical manifestations.
RESULTS
One 45-year-old man presented with fever, blood leukocytosis with neutrophilia, maculopapular skin rash and pustular formation, which developed after eating lacquer chicken. Severe hypotension and later elevated hepatic enzymes were accompanied. Patch test to undiluted lacquer was positive. The other 48-year-old man was admitted with fever, maculopapular skin rash and subsequent pustular formation and blood leukocytosis with neutrophilia following ingestion of lacquer chicken. One week later, blood eosinophilia and elevated liver enzymes were found.
CONCLUSION
AGEP may be caused by ingestion of lacquer chicken via Type IV immune hypersensitivity and can be accompanied by hypotension, blood eosinophilia and/or abnormal hepatic function.

MeSH Terms

Acute Generalized Exanthematous Pustulosis
Chickens
Eating
Eosinophilia
Exanthema
Fever
Food Hypersensitivity
Humans
Hypersensitivity
Hypotension
Lacquer
Leukocytosis
Liver
Middle Aged
Patch Tests