Ewha Med J.  1988 Mar;11(1):49-57. 10.12771/emj.1988.11.1.49.

Experimental Study on Microvascular Anastomosis without Sutures Using Fibrin Glue

• Yoon CH
• Kim HJ

• KMID: 1965743
• DOI: http://doi.org/10.12771/emj.1988.11.1.49

Abstract

Since the anastomosis by suture, most widely used in microvascular surgery, has two major disadvantage in that it may inflict considerable damage on the vessel ends and that the suture material may function as a thrombogenic agent, much effort has been spent in developing methods of anastomosis in which the number of suture is reduced to minimum. As one of such efforts, we performed the following experiment using fibrin glue leaving out any suture material. First we divided the femoral artery of the rat and telescoped the proximal end into distal end by traction of two U-shaped guide sutures. Next, we removed the guide sutures and dropped the fibrinogen and thrombin solution dissolved in the distilled water and calcium chloride respectively on the telescoped area. After waiting for 5 minutes, vascular clamps were released. The result we got from the gross and histological examination showed that this method has advantage as follows; 1)This method is easier and speedier than suture technique. 2)Suture material was not exposed into the lumen. 3)There was less vessel trauma owing to fewer sutures and less manipulation of the vessel end. 4)Blood leakage from the anastomosal site was prevented. 5)There was no aneurysm.

MeSH Terms

Aneurysm
Animals
Calcium Chloride
Femoral Artery
Fibrin Tissue Adhesive*
Fibrin*
Fibrinogen
Rats
Suture Techniques
Sutures*
Thrombin
Traction
Water
Calcium Chloride
Fibrin
Fibrin Tissue Adhesive
Fibrinogen
Thrombin
Water