Ewha Med J.
2007 Mar;30(1):61-66. 10.12771/emj.2007.30.1.61.
A Case of Hepatoid Adenocarcinoma without Involving Liver Parenchyme
- Affiliations
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- 1Department of Internal Medicine, Ewha Womans University College of Medicine, Korea.
- 2Department of General Surgery, Ewha Womans University College of Medicine, Korea.
- 3Department of Pathology, Ewha Womans University College of Medicine, Korea.
- KMID: 1963360
- DOI: http://doi.org/10.12771/emj.2007.30.1.61
Abstract
- Hepatoid adenocarcinoma was described by Ishikura in 1985 for the first time. It is a very rare variant of adenocarcinoma characterized by morphological and functional features of hepatocyte differentiation. It is most commonly presented as gastric adenocarcinoma with otherwise unexplained elevation of serum alpha-fetoprotein level. Most of the patients with gastric hepatoid adenocarcinoma were diagnosed in advanced stages having vascular invasion and/or extensive metastasis in liver or lymph nodes. Accordingly, the prognosis of hepatoid adenocarcinoma is dismal. We experienced a typical case of gastric hepatoid adenocarcinoma and described the clinical features.
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