J Korean Neurosurg Soc.  1995 Dec;24(12):1594-1599.

Surgical Experience of Intracranial Aneurysm in a Patient with Polycystic Kidney: Case Report

• Hur W
• Park HS
• Kim SY
• Lee DY

Abstract

Rupture of cerebral aneurysm is a significant cause of morbidity and mortality in patients with polycystic kidney. Although many authors have emphasized the relationship between these two diseases, the exact pathogenesis has yet to be identified yet. Recently a number of authors have emphasized the defect of chromosome 16 as the basis of pathogenesis of these disease. We have treated surgically a case of P2-3 junction aneurysm in a 44 year-old male with bilateral polycystic kidneys. While abdominal ultrasonograph had revealed multiple microcysts of the liver, four vessel angiographies futher revealed marked arteriosclerotic changes of cerebral arteries. The aneurysmal neck was successfully clipped through subtemporal approach resulting in good outcome. The above mentioned cases of cerebral aneurysm with polycystic kidney will be discussed with respect to its pathogenesis and treatment modality along with literature review.

Keyword

Polycystic kidney; Intracranial aneurysm

MeSH Terms

Adult
Aneurysm
Angiography
Cerebral Arteries
Chromosomes, Human, Pair 16
Humans
Intracranial Aneurysm*
Liver
Male
Mortality
Neck
Polycystic Kidney Diseases*
Rupture