J Korean Ophthalmol Soc.  1991 Mar;32(3):327-330.

Septo-optic dysplasia

Affiliations
  • 1Department of Ophthalmology, College of Medicine Seoul National University, Seoul, Korea.

Abstract

Septo-optic dysplasia, first described by de Morsier in 1956, is an uncommon congenital midline structural abnormality of the brain, including agenesis of septum pellucidum, primitive optic ventricle and dysplasia of the optic chiasm, optic nerves, and infundibulum. Agenesis of septum pellucidum, initially thought to be an integral part of this syndrome, is inconstant and not an essential part of the disorder. Also, it reveals a variable spectrum of associated abnormalities in disturbed hypothalamic-pituitary function. We recently experienced 3 patients of septo-optic dysplasia who showed bilateral optic disc hypoplasia clinically and midline structural abnormalities in computerized tomography(CT) or magnetic resonance imaging(MRI).

Keyword

Septo-optic dysplasia; septum pellucidum; optic disc hypoplasia; hypothalamic ipituitary function

MeSH Terms

Brain
Humans
Optic Chiasm
Optic Nerve
Septo-Optic Dysplasia*
Septum Pellucidum
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error