J Korean Ophthalmol Soc.  1981 Jun;22(2):395-398.

Superior Limbic Keratoconjunctivits

  • 1Department of Ophthalmology, Yonsei University, College of Medicine, Seoul, Korea.


Superior limbic keratoconjunctivits (SLK) is a chronic, recurrent keratoconjunctivitis of unknown etiology, which is clinically characterized by papillary hypertrophy of upper tarsus, redness of the superior bulbar conjunctiva, thickening and keratinization of the superior limbus, epithelial keratitis. recurrent filaments formation, and superior micropannus. This. disease may be bilateral and usually common in females between 20 and 60 years of age. Superior limbic keratoconjunctivitis does not respond to topical antibiotics, antivirals, nor corticosteroids. A 28 year old Korean male was found to have characteristic clinical signs of superior limbic keratoconjunctivitis O.U. which was confirmed on the scraping by demonstrating keratinizing and degenerating epithelial cells of the limbus. No thyroid disease was seen in association with superior limbic keratoconjunctivitis. Application of 0.5% silver nitrate solution improved the condition of superior limbic keratoconjunctivitis.

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