J Korean Pain Soc.  2003 Jun;16(1):101-104.

The Effect of an Oral Ketamine on Post-herpetic Neuralgia: A case report

  • 1Department of Anesthesiology and Pain Medicine, Soonchunhyang University Hospital, Bucheon, Korea. yikim@schbc.ac.kr


Post-herpetic neuralgia is a kind of neuropathic pain that severely annoys patients all their life. Many remedies are now available, but a panacea does not exist. Ketamine, a non-competitive N-methyl- D-aspartate (NMDA) receptor antagonist, has been used for analgesia in many pain syndromes, including post-herpetic neuralgia. The routes of administration are variable, but intravenous and intraspinal options are popular. Oral ketamine has been used effectively in a variety of pain syndromes, as well as in the premedication of children, or psychiatrically problemed patients. We applied oral ketamine (0.3-0.7 mg/kg), with a continuous intravenous infusion of low dose ketamine (0.1-0.2 mg/kg), to post-herpetic neuralgia patients. The patients reported various effects of the oral ketamine.


Ketamine; Post-herpetic neuralgia
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