J Korean Soc Radiol.  2015 Apr;72(4):295-299. 10.3348/jksr.2015.72.4.295.

Bilateral Presentation of Pleural Desmoplastic Small Round Cell Tumors: A Case Report

Affiliations
  • 1Department of Radiology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Korea. jspark@schmc.ac.kr
  • 2Department of Pathology, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Korea.

Abstract

Desmoplastic small round cell tumor (DSRCT) is a highly aggressive malignant small cell neoplasm occurring mainly in the abdominal cavity, but it is extremely rare in the pleura. In this case, a 15-year-old male presented with a 1-month history of left chest pain. Chest radiographs revealed pleural thickening in the left hemithorax and chest computed tomography showed multifocal pleural thickening with enhancement in both hemithoraces. A needle biopsy of the left pleural lesion was performed and the final diagnosis was DSRCT of the pleura. We report this unusual case arising from the pleura bilaterally. The pleural involvement of this tumor supports the hypothesis that it typically occurs in mesothelial-lined surfaces.


MeSH Terms

Abdominal Cavity
Adolescent
Biopsy, Needle
Chest Pain
Desmoplastic Small Round Cell Tumor*
Diagnosis
Humans
Male
Pleura
Radiography, Thoracic
Thorax

Figure

  • Fig. 1 Chest radiographs (A, B), chest CT (C-E), and microscopic features (F-H) of desmoplastic small round cell tumor in a 15-year-old male. A, B. Chest radiograph posteroanterior (A) and left lateral decubitus (B) views show a soft tissue mass (arrow) at the left mid hemithorax. C, D. Transverse CT image of the chest shows multifocal pleural plaque with enhancement in both hemithoraces (left hemithorax, arrow; right hemithorax, arrowhead). E. Coronal reformatted CT image shows a pleural plaque at the lateral aspect of the left hemithorax. F. Photomicrograph of hematoxylin and eosin-stained specimen (× 100) shows cellular small round cell nests within dense fibrous stroma. G, H. Positive immunoreactivity for CD56 (× 200) (G) and vimentin (× 200) (H) is seen on the tumor cell membranes.


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