J Menopausal Med.  2013 Dec;19(3):139-142. 10.6118/jmm.2013.19.3.139.

A Case of Vaginal Cancer with Uterine Prolapse

• Kim HG
• Song YJ
• Na YJ
• Choi OH

• KMID: 1939538
• DOI: http://doi.org/10.6118/jmm.2013.19.3.139

Abstract

Primary vaginal cancer combined with uterine prolapse is very rare. We present a case of 80-year-old postmenopausal women complaints of something coming out per vagina for the past 20 years, along with blood stained discharge, foul odor leukorrhea, and severe pelvic pain for the last 3 months. A 4 x 5 cm ulcer was present on middle third of vaginal wall with marked edema and ulceration of surrounding tissue. The prolapse was reduced under intravenous sedation in operating room. On gynecologic examination, uterus was normal in size, no adnexal mass was examined, and both parametrium were thickened. Papanicolaou smear was normal. Biopsy of the ulcer at vaginal wall revealed invasive squamous cell carcinoma of vagina. Magnetic Resonance Imaging of abdomen and pelvis showed left hydronephrosis and liver metastasis. Positron emission tomography (PET)/computed tomography (CT) revealed metastasis to lung, liver and iliac bone. She died from progression of disease one month after diagnosis.

Keyword

Postmenopause; Uterine prolapse; Vaginal neoplasms

MeSH Terms

Abdomen
Aged, 80 and over
Biopsy
Blood Stains
Carcinoma, Squamous Cell
Diagnosis
Edema
Female
Humans
Hydronephrosis
Leukorrhea
Liver
Lung
Magnetic Resonance Imaging
Neoplasm Metastasis
Odors
Operating Rooms
Papanicolaou Test
Pelvic Pain
Pelvis
Positron-Emission Tomography
Postmenopause
Prolapse
Ulcer
Uterine Prolapse*
Uterus
Vagina
Vaginal Neoplasms*

Figure

• 

  Fig. 1 Histopathology of biopsied specimen showing squamous cell carcinoma of the vagina (H & E, × 200).

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  Fig. 2 (A) A high signal intensity lesion at posterior vagina in T2-weighted sagittal magnetic resonance imaging (MRI) image. (B) A liver metastasis in T2-weighted axial MRI image. (C) A Left hydronephrosis T2-weighted axial MRI image.

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  Fig. 3 Multiple hypermetabolic lesion at lung, liver and iliac bone in positron emission tomography/computed tomography.

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