Korean J Anesthesiol.  1996 Jun;30(6):724-732. 10.4097/kjae.1996.30.6.724.

Correlation of Mixed Venous and Central Venous Oxygen Saturation and Comparison between Venous-Oxygen Saturation and Cardiac Index

• Song SO
• Cheun MH

• KMID: 1934805
• DOI: http://doi.org/10.4097/kjae.1996.30.6.724

Abstract

BACKGROUND: Although mixed venous oxygen saturation(SvO2) has been established as a useful measure of whole body oxygenation, SvO2 must be measured through a pulmonary artery(PA) catheter. We performed this study to evaluate whether central venous oxygen saturation(ScvO2) could substitute for SvO2, and whether SvO2 reflects cardiac output.
METHODS
Twenty five patients were studied. Thirteen patients(GA Group) had PA catheters inserted during general anesthesia, and twelve(ICU Group) patients in the intensive care unit had PA catheters inserted for management of critical illnesses. In each patient, blood samples for SvO2 and ScvO2 were drawn separately from the PA and CVP ports of a PA catheter, and cadiac index(CI) was measured.
RESULTS
Mean ScvO2 was significantly higher than SvO2 in both group, but the differences of SvO2 and ScvO2 were only about 2.5%. Correlations of SvO2 and ScvO2 were very high in GA and ICU Groups(r=0.92, 0.95, respectively). SvO2 was weakly related to CI in GA Group(r=0.64), and in ICU Group(r=0.50)
CONCLUSIONS
We conclude that ScvO2 can be a useful estimate of SvO2, but SvO2 does not reliably reflect cardiac index.

Keyword

Equipment; catheter; pulmonary arterial; Monitoring; cardiac index; central and mixed venous oxygen saturation

MeSH Terms

Anesthesia, General
Cardiac Output
Catheters
Critical Illness
Humans
Intensive Care Units
Oxygen*
Oxygen