The Effect of Arterial and Venous Blood Oxygen Pressure on the Blood Glucase Value

Kim, Yu Hee; Lee, Choon Hi

Abstract

BACKGROUND: The portable glucose meter is useful in operating rooms and intensive care units (ICUs), where blood glucose concentration must be analyzed frequently and rapidly, and provides immediate information for clinical decisions. At present, the glucose-oxidase(GOD) method is used extensively among many glucose measurement methods but blood oxygen concentration affects this blood glucose value because oxygen, at increased concentration, consumes blood glucose which cannot then be measured by GOD method. The purpose of this study is to investigate the effect of blood oxygen pressure on the blood glucose value by GOD method by the comparison of arterial and venous blood glucose values. METHOD: Patients are randomly assigned to FiO2. 0.33(group1; n=15), FiO2 0.5(group2; n=15) and FiO2 1.0(group3; n=15) groups. 20 minutes after intubation, the samples were obtained from artery and vein. Blood glucose concentrations were measured by portable glucose meter, respectively. RESULT: The value of arterial blood glucose when measured by the GOD method could be underestimated more than the value of venous blood glucose by 3~5 mg/dl.
CONCLUSION
The blood glucose value obtained by GOD method is certainly affected by increased blood oxygen pressure. The underestimation is not a clinical problem when blood glucose is high, but anesthesiologist should pay attention to hypoglycemia by the GOD method when blood oxygen pressure is high.