Korean J Dermatol.  2007 Apr;45(4):404-406.

A Case of Vitamin K1 Dermatitis due to Intralesional Injection for Cosmetic Purpose

Affiliations
  • 1Department of Dermatology, Eulji General Hospital, Collage of Medicine, Eulji University, Korea. ssjmdderma@eulji.or.kr
  • 2Department of Dermatology, Reborn Dermatology Clinic, Seoul, Korea.

Abstract

Vitamin K is a lipid-soluble vitamin used in the treatment of hypoprothrombinemia found in diseases of the liver, biliary tract and small intestine. Vitamin K1 (Phytonadione) is the natural form of vitamin K. Recently, a cream containing vitamin K1 has been marketed for topical use in the treatment of periorbital hyperpigmentation, telangiectasia and rosacea. Vitamin K1 dermatitis is a cutaneous adverse reaction to vitamin K1 and can cause acute pruritic, erythematous, eczematoid, indulated plaques or slowly-appearing sclerodermatous plaques. We present a case of dermatitis caused by a vitamin K1 intralesional injection for treatment of facial telangiectasia and flushing.

Keyword

Vitamin K1 dermatitis; Phytonadione

MeSH Terms

Biliary Tract
Dermatitis*
Flushing
Hyperpigmentation
Hypoprothrombinemias
Injections, Intralesional*
Intestine, Small
Liver
Rosacea
Telangiectasis
Vitamin K
Vitamin K 1*
Vitamins*
Vitamin K
Vitamin K 1
Vitamins
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