Korean J Gastrointest Endosc.  2002 Jul;25(1):38-42.

A Case of Gastrointestinal Amyloidosis Presenting with Hematochezia

Affiliations
  • 1Division of Gastroenterology, Department of Internal Medicine, Chungbuk National University College of Medicine, Cheong-Ju, Chung-buk, Korea. sjyoun@med.chungbuk.ac.kr
  • 2Department of Pathology, Chungbuk National University College of Medicine, Cheong-Ju, Chung-buk, Korea.
  • 3Department of Radiology, Chungbuk National University College of Medicine, Cheong-Ju, Chung-buk, Korea.

Abstract

Amyloidosis is a disorder of protein metabolism that leads to extracellular deposition of amyloid in tissues and organs. Multiple organ dysfunction can be induced by deposition of amyloid. Diagnosis is established by histologic demonstration of amyloid protein in involved tissue using Congo red staining. A 72 year-old woman was admitted due to mild abdominal pain, diarrhea and hematochezia. Duodenoscopic and colonoscopic findings were nonspecific, however, multiple biopsies showed amyloid deposits characterized by green birefringence under polarized light. The findings of small bowel series and abdominal CT were compatible with amyloidosis. We experienced a case of amyloidosis with involvement of the whole bowel.

Keyword

Gastric; Small bowel and colonic amyloidosis

MeSH Terms

Abdominal Pain
Aged
Amyloid
Amyloidosis*
Biopsy
Birefringence
Congo Red
Diagnosis
Diarrhea
Female
Gastrointestinal Hemorrhage*
Humans
Metabolism
Plaque, Amyloid
Tomography, X-Ray Computed
Amyloid
Congo Red
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