Korean J Gastrointest Endosc.  2005 Mar;30(3):173-177.

A Case of Rectal Gastrointestinal Stromal Tumor with Bleeding

• Shin JA
• Kim SJ
• Shin WC
• Lee JH
• Choi WC
• Kim KY
• Jeong MJ
• Lim SJ

Abstract

Gastrointestinal stromal tumors (GIST), although uncommon mesenchymal tumors of the gastrointestinal tract, are occasionally encountered on endoscopic examination. GIST can be found all gastrointestinal tract, but rare in the rectum. We report a 72-year-old woman presented with intermittent bloody stool for a year. On rectal examination, a firm fixed mass was felt on the anterior wall of the rectum. Computed tomography revealed the 4.8x4.5 cm sized exophytic and centrally depressed mass on the rectum without the evidence of adjacent organ invasion or metastasis. On colonoscopic examination, there was a round elevated lesion having central ulcer with adherent blood clots. Endoscopic deep biopsy examination revealed a submucosal tumor consisting of spindle cells with elongated cigar-shaped nuclei arranged in fascicles and whorls. Mitotic counts were fewer than 5 per 50 high-power fields. The tumor cells were positive for KIT and CD34 immunohistostaining and negative for SMA. Local excision recommended, but the patient discharged against the advice.

Keyword

GIST; Rectum; KIT; CD34

MeSH Terms

Aged
Biopsy
Female
Gastrointestinal Stromal Tumors*
Gastrointestinal Tract
Hemorrhage*
Humans
Neoplasm Metastasis
Rectum
Ulcer