Korean J Gastrointest Endosc.  2000 Apr;20(4):312-316.

Two Cases of Duodenal Metastasis from Lung Cancer with Obstructive Jaundice

• Min YI
• Lee SK
• Kim MH
• Seo DW
• Yoo KS
• Ju YH
• Lee KA
• Park JS
• Yoo CS

Abstract

Lung cancer metastatic to the small intestine is uncommon. Despite the widespread nature of metastases that characterize this carcinoma, symptomatic intestinal metastases are extremely rare, but have been reported as a cause of intestinal obstruction, hemorrhage, malabsorption, and perforation. We have recently encountered two cases with squamous cell lung cancer who underwent endoscopic retrograde cholangiopancreatography for obstructive jaundice. Biopsies obtained from concentric ulcerative mass in the duodenum showed metastatic squamous cell carcinoma in the lymphatics. Histologically, the pulmonary and duodenal lesions were identical and this suggests a lymphatic route of dissemination. This is the report of two cases with obstructive jaundice secondary to duodenal metastasis from primary lung cancer. Metastatic squamous cell carcinoma of the lung to the duodenum should be considered in the differential diagnosis of patients harboring such a malignancy who have obstructive jaundice.

Keyword

Lung cancer; Jaundice; Duodenal metastasis

MeSH Terms

Biopsy
Carcinoma, Squamous Cell
Cholangiopancreatography, Endoscopic Retrograde
Diagnosis, Differential
Duodenum
Hemorrhage
Humans
Intestinal Obstruction
Intestine, Small
Jaundice
Jaundice, Obstructive*
Lung Neoplasms*
Lung*
Neoplasm Metastasis*
Ulcer