Korean J Gastrointest Endosc.  1991 Nov;11(2):383-386.

A Case of Colonoscopically Removed Granular Cell Tumor in the Ascending Colon

Abstract

This case report describes a patient with semipedunclated granuylar cell tumor(granular cell myoblastoma) of the proximal ascending colon removed by endoscopic polypectomy. A 39-year old femalie was visited to our hospital for intermittent abdominal pain and loose stool. Colonoscopic examination showed a semipedunclated lesion covered with yellowish white smooth mucosa in the proximal ascending colon. The tumor was removed by endoscopic polypectomy. The collected specimen was 0.9x0.8 cm in size. The cut surface of the specimen showed a white round firm tumor covered with mormal epithelium of the colon. Using immunohistochemical study, the tumor cells were to be positively stained by S-100 protein and negatively stained by desmin, which supports the concept of the Schwann cell origin of granular cell tumor. In Korea, 2 cases of granular cell tumor of the colon and rectum, which were treated by surgical removal, have been reported. This case in the first endoscopic polypectomy of granular cell tumor of the colon and retum in Korea. The endoscopic polypectomy is thought to be useful for the therapy of small pedunclated or semipedunclated granular cell tumor, intracolonic type.

Keyword

Granular cell tumor; Colon; Endoscopic polypectomy; Schwann cell origuin; S-100 protein staining

MeSH Terms

Abdominal Pain
Adult
Colon
Colon, Ascending*
Desmin
Epithelium
Granular Cell Tumor*
Humans
Korea
Mucous Membrane
Rectum
S100 Proteins
Desmin
S100 Proteins
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