Korean J Urol.  1995 Sep;36(9):1003-1006.

Small Cell Carcinoma of the Kidney with Spontaneous Rupture of the Kidney

Affiliations
  • 1Department of Urology, National Police Hospital, Seoul, Korea.
  • 2Department of Pathology, National Police Hospital, Seoul, Korea.
  • 3Department of Pathology, College of Medicine, Han Yang University, Seoul, Korea.

Abstract

Small cell carcinoma of the kidney is very rare, but lethal due to early metastasis and rapid progression. We report a case of the primary small cell carcinoma of the kidney with large rena1 calculus resulting in spontaneous rupture of the kidney, and was managed by total nephrectomy and evacuation of retroperitoneal hematoma and calculus. Immunohistochemical studies revealed the positive staining for cytokeratin and neuron-specific enolase, and dense-core neurosecretory granules were identified in the cytoplasm by electron microscopy. This report is the first case of the primary small cell carcinoma of the kidney resulting in spontaneous rupture of the kidney.

Keyword

Small cell carcinoma; Kidney; Spontaneous rupture

MeSH Terms

Calculi
Carcinoma, Small Cell*
Cytoplasm
Hematoma
Keratins
Kidney*
Microscopy, Electron
Neoplasm Metastasis
Nephrectomy
Phosphopyruvate Hydratase
Rupture, Spontaneous*
Keratins
Phosphopyruvate Hydratase
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