Korean J Urol.  1984 Oct;25(5):663-669.

Clinical Observation on Adrenogenital Syndrome

Affiliations
  • 1Department of Urology, Chonnam University, Medical School, Kwangju, Korea.

Abstract

A clinical observation was made on patients of congenital adrenogenital syndrome who had been admitted to the Department of Urology, Chonnam University Medical School during the period from January 1972 to June 1984. The following results were obtained : 1. Cases of adrenogenital syndrome were 6 of 3,170 total urologic in-patients giving ratio of 0.2%. The ratio of female to male is 5: 1. 2. Presenting symptoms were enlarged clitoris or penis and abundant pubic hair in all cases, acne and deep voice in 4 cases, amenorrhea in 3 cases. 3. Blood pressure and serum level of sodium and potassium were within normal limit in all cases. 4. Urinary 17 ketosteroid was elevated in all cases. On dexamethasone suppression test the amount of urinary 17 ketosteroid dropped to a value below two-thirds of the pretest level in all cases 5. Vaginoplasty and clitoroplasty were performed at the same time in 5 of 6 cases. All cases were to be given dexamethasone for life time. 6. Menstruation and breast development occurred two months after initiation of dexamethasone therapy in 3 cases.

Keyword

adrenogenital syndrome

MeSH Terms

Acne Vulgaris
Adrenogenital Syndrome*
Amenorrhea
Blood Pressure
Breast
Clitoris
Dexamethasone
Female
Hair
Humans
Jeollanam-do
Male
Menstruation
Penis
Potassium
Schools, Medical
Sodium
Urology
Voice
Dexamethasone
Potassium
Sodium
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