Prog Med Phys.  2013 Sep;24(3):183-190. 10.14316/pmp.2013.24.3.183.

Development of Photoacoustic System for Breast Cancer Detection

• Lee S
• Ji YS
• Lee R

• KMID: 1910583
• DOI: http://doi.org/10.14316/pmp.2013.24.3.183

Abstract

Recently, the photoacoustic imaging system has been widely and intensively developed, and has been shown the possibility of diagnosis for early stage cancer. In this study, we developed a photoacoustic tomography imaging system with a commercial ultra sound device and a linear array probe. A tube phantom and a chicken breast phantom was made for the possibility of a system as a breast cancer detection. A moving average filter and a band pass filter with 3~6 MHz bandwidth were developed for background noise elimination before delay-and-sum beamforming algorithm was used for image reconstruction. As a result, we showed that some signal processing procedure before beamforming was effective for the photoacoustic image reconstruction.

Keyword

Photoacoustic tomography; Linear array transducer; Breast cancer

MeSH Terms

Breast Neoplasms*
Breast*
Chickens
Diagnosis
Image Processing, Computer-Assisted
Noise

Figure

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  Fig. 1. Photoacoustic imaging system.

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  Fig. 2. (a) Silicon tube phantom filled with methylene blue, (b) Chicken breast phantom inserted with silicon tube filled with methylene blue, (c) Measurement of tube phantom by probe module, (d) Measurement of chicken breast phantom by probe module.

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  Fig. 3. (a) Ultra sound image of tube phantom, (b) Photoacoustic signal of tube phantom, (c) Reconstructed image by DAS algorithm, (d) XY plane reconstructed image by 3D scanning.

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  Fig. 4. 3D scanning method. (a) Y-axis scanning. (b) Photoacoustic image of x-z image. (c) Reconstructed x-y plane image of a fixed z-depth.

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  Fig. 5. Reconstructed image of chicken breast phantom with signal processing and without signal processing.

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  Fig. 6. Fusion of ultrasound and photoacoustic image of chicken breast phantom.

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