J Korean Cancer Assoc.  1997 Jun;29(3):516-521.

A Case of Acute Myelogenous Leukemia during Pregnancy

Affiliations
  • 1Department of Internal Medicine, DanKook University Medical College, Cheonan, Korea.

Abstract

The incidence of acute leukemia in pregnancy is rare. The treatment of acute leukemia during pregnancy is complicated and therapeutic options must be made with each individual patient. Complete remission can now be achieved in 60 to 70% of previously untreated adults with acute myelogenous leukemia (AML). Antileukemic chemotherapy can be administered safely during the second and third trimesters. Cytarabine (ara-C) and anthracycline has not been associated with birth defect. When a pregnant woman presents with acute leukemia, chemotherapy should be recommended as vigorously as in the non- pregnant woman. We reported a case of AML during pregnancy. The patient recieved induction chemotherapy with ara-C and idarubicin. The baby was delivered at 33 weeks of gestation and had transient neutropenia. The mother received consolidation chemotherapy after achievement of complete remission.

Keyword

Acute myelogenous leukemia; Pregnancy

MeSH Terms

Adult
Congenital Abnormalities
Consolidation Chemotherapy
Cytarabine
Drug Therapy
Female
Humans
Idarubicin
Incidence
Induction Chemotherapy
Leukemia
Leukemia, Myeloid, Acute*
Mothers
Neutropenia
Pregnancy Trimester, Third
Pregnancy*
Pregnant Women
Cytarabine
Idarubicin
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