Korean J Gastrointest Endosc.  2001 Feb;22(2):76-82.

Clinical Patterns and Prognostic Factors of Ischemic Colitis

Affiliations
  • 1Department of Internal Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 2Department of Diagnostic Radiology, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 3Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

BACKGROUND/AIMS: Colonic ischemia is recognized as the most common vascular disorder of the intestines in the elderly. The severity of the disease may vary considerably with the prevalent benign transient forms, being amenable to conservative treatments and the severe gangrenous forms, requiring surgery. Correct diagnosis is usually made after the ischemic episode is over and colonic ischemia is frequently misdiagnosed. The aim of this study is to identify the clinical patterns and prognostic factors of ischemic colitis.
METHODS
We found 60 patients with nonoccusive ischemia of the large intestine. We analyzed age, sex, symptoms, signs, associated disease, location, endoscopy, hematologic, histologic, radiologic finding and treatment, retrospectively.
RESULTS
The mean age was 60.2+/-16.3 years. The most common symtoms were abdominal pain or bloody diarrhea. The most common sign was diffuse abdominal tenderness. The most common hematologic findings were anemia and leukocytosis. Associated medical illnesses were diabetes, rhematoid arthritis and cerebrovascular accident, et al. Both computed tomography (CT) and endoscopy were useful diagnostic tools. The most common involved site was sigmoid colon. 46 patients were treated conservatively and 14 patients were managed surgically.
CONCLUSIONS
Male gender, those with rebound tenderness, severe anemia, right or total colon involvement as well as rheumatoid arthritis had a poor prognosis. Both CT and endoscopy were useful in predicting prognosis.

Keyword

Ischemic colitis; Clinical patterns; Prognostic factors

MeSH Terms

Abdominal Pain
Aged
Anemia
Arthritis
Arthritis, Rheumatoid
Colitis, Ischemic*
Colon
Colon, Sigmoid
Diagnosis
Diarrhea
Endoscopy
Humans
Intestine, Large
Intestines
Ischemia
Leukocytosis
Male
Prognosis
Retrospective Studies
Stroke
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