Korean J Gastrointest Endosc.  2001 Feb;22(2):70-75.

Diagnosis of Helicobacter pylori Infection by Pronto Dry Test

Affiliations
  • 1Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Seoul, Korea.
  • 2Department of Pathology and Institute for Digestive Research, Soon Chun Hyang University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND/AIMS: Pronto Dry test, a new rapid urease test, is consisted of a dry filter paper containing urea and has been reported to have a more rapid reaction time than others. We performed this study to compare the accuracy of Pronto Dry test with the other conventional tests for detection of H. pylori.
METHODS
One hundred patients underwent gastroscopy in our hospital for gastrointestinal symptoms. Biopsy specimens were taken for Pronto Dry test, polymerase chain reaction, culture, and histologic examination (Warthin-Starry stain). 13C-urea breath test was also performed. The results of Pronto Dry test were read after 1 hour.
RESULTS
The sensitivity, specificity, positive and negative predictive value of Pronto Dry test to diagnose H. pylori infection were 90.0%, 100%, 100%, and 90.9%, respectively. The kappa statistic between H. pylori status and Pronto Dry test was 0.90, demonstrating an acceptable level of reliability.
CONCLUSIONS
Pronto Dry test has a high sensitivity and specificity, and can be used as a rapid test to diagnose H. pylori infection.

Keyword

Pronto Dry test; Rapid urease test; Helicobacter pylori

MeSH Terms

Biopsy
Breath Tests
Diagnosis*
Gastroscopy
Helicobacter pylori*
Helicobacter*
Humans
Polymerase Chain Reaction
Reaction Time
Sensitivity and Specificity
Urea
Urease
Urea
Urease
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