Korean J Gastrointest Endosc.  2001 Jun;22(6):428-430.

A Case of Gastric Langerhans Cell Histiocytosis Showing Hypertrophic Folds

Affiliations
  • 1Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea

Abstract

Langerhans cell histiocytosis is a rare disease entity in which various tissue are infiltrated by proliferating histiocytes. Involvement of alimentary tract is rare (<5%), especially in the stomach. Only seven cases of gastric Langerhans cell histiocytosis have been reported in Enlglish literature. Diabetes insipidus is the most common endocrinologic complication. We report a case of Langerhans cell histiocytosis involving stomach and pituitary stalk. The diagnosis of gastric Langerhans cell histiocytosis and diabetes insipidus was based on gastric mucosal biopsy specimen from a Korean man with suspicious hypertrophic gastric folds of gastric body, water deprivation test and sella MRI.

Keyword

Langerhans cell histiocytosis; Stomach; Diabetes insipidus

MeSH Terms

Biopsy
Diabetes Insipidus
Diagnosis
Histiocytes
Histiocytosis, Langerhans-Cell*
Magnetic Resonance Imaging
Pituitary Gland
Rare Diseases
Stomach
Water Deprivation
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