Korean J Otolaryngol-Head Neck Surg.  1999 May;42(5):652-655.

Invasive Aspergillosis of the Maxillary Sinus Invading Skull Base: Report of a Case

  • 1Department of Otolaryngology, Asan Medical Center University of Ulsan College of Medicine, Seoul, Korea. yjkim@www.amc.seoul.kr


Previously healthy 66 year-old woman visited complaining of a severe continous, intractable right-sided frontotemporal headache. She had been diagnosed with fungal sinusitis of the right maxillary sinus from another hospital 6 months ago and had undergone Caldwell-Luc operation without symptom improvement. Her immunologic status was normal and she was healthy and without an underlying DM or oncologic problems. PNS CT finding shows aggressive fungal sinusitis involving maxillary sinus and pterygopalatine fossa and inferior wall of right orbit. Biopsy showed fungal hyphe of Aspergillus species. Right medial maxillectomy via midfacial degloving approach was done and intravenous amphotericin-B therapy of 55 mg/day was carried out for 6 weeks (2.0 gm) in total postoperatively. Follow-up PNS CT showed no recurred lesion in the right maxillary region twelve months postoperatively.


Invasive aspergillosis; Maxillectomy
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