Korean J Otolaryngol-Head Neck Surg.  2005 Sep;48(9):1181-1184.

Carcinoma Ex Pleomorphic Adenoma Including Malignant Component of Adenoid Cystic Carcinoma in the Parotid Gland

• Lee SK
• Kim SW
• Yeo SG
• Cho JS

Abstract

Carcinoma ex pleomorphic adenoma is rare, aggressive, poorly understood malignancy that occurs in the salivary glands. In carcinoma ex pleomorphic adenoma, an epithelial malignancy develops in association with primary or recurrent benign pleomorphic adenoma. The patient was a 37-year-old female with slow-growing preauricular mass that has been present for 2 years. She visited the hospital because of sudden increase of mass size. The initial cytologic finding by fine needle aspiration biopsy showed what was probably a benign tumor and the radiologic finding revealed a 2.0x1.9 cm sized mass without cervical lymphadenopathy. After right superficial parotidectomy, the histologic examination revealed that tumor was composed of epithelial and mesenchymal component of pleomorphic adenoma and cribriform areas mimicking adenoid cystic carcinoma. Additionally, we did right near-total parotidectomy and postoperative radiotheraphy for 6 weeks. We present a rare case of carcinoma ex pleomorphic adenoma including adenoid cystic component in the parotid gland.

Keyword

Carcinoma ex pleomorphic adenoma; Parotid gland; Adenoid cystic carcinoma

MeSH Terms

Adenoids*
Adenoma, Pleomorphic*
Adult
Biopsy
Biopsy, Fine-Needle
Carcinoma, Adenoid Cystic*
Female
Humans
Lymphatic Diseases
Parotid Gland*
Salivary Glands