Korean J Med.  2004 Mar;66(3):288-292.

A case of bronchiolitis obliterans organizing pneumonia in patient with systemic lupus erythematosus

  • 1Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. ksimd@pusan.ac.kr


Pleuropulmonary manifestations of systemic lupus erythematosus (SLE) are protean and include pleuritis, pulmonary nodule, chronic interstitial pneumonitis, pulmonary hypertension, pulmonary embolism, alveolar hemorrhage, bronchiolitis obliterans (with or without organizing pneumonia), and opportunistic pulmonary infections. Although bronchiolitis obliterans organizing pneumonia (BOOP) has been associated with several connective tissue disorders, there are rare repots of BOOP in patients with SLE. We present a patient with SLE who complained cough and exercise induced dyspnea. Simple chest radiography and high resolution computed tomography (HRCT) of lung were consistent with BOOP and thoracoscopic lung biopsy showed BOOP. Clinical symptoms and radiographic findings were improved after treatment with methylprednisolone pulse and intravenous cyclophosphamide pulse therapy.


Systemic lupus erythematosus (SLE); Bronchiolitis obliterans organizing pneumonia(BOOP)
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