Korean J Gastrointest Endosc.  2001 Dec;23(6):431-436.

The Study of Pathologic Difference between Endoscopic Biopsy before EMR and Histology of Specimen after Endoscopic Mucosal Resection (EMR) on Gastric Flat Adenoma or Early Gastric Cancer (EGC)

• Park HK
• Cheon YK
• Jung HK
• Park HJ
• Cho JY
• Cheon GJ
• Jung IS
• Kim JO
• Lee JS
• Jin SY
• Shim CS

Abstract

BACKGROUND/AIMS: It is not uncommon to show discrepancy between the histology of the endoscopic biopsy and that of the resected specimen obtained from the same lesion by EMR. The aim of this study was to ascertain whether routine endoscopic biopsy specimens are sufficient to qualify the representative enough to reliable indication of EMR.
METHODS
We retrospectively reviewed 36 cases that could be compared the histologic results from the resected specimens by EMR to the tissue obtained by endoscopic biopsy. The histologic slides were reviewed by one pathologist.
RESULTS
Of the 36 cases, 13 cases of EGC and 23 cases of gastric flat adenomas were included. Among 13 cases of EGC, 2 case (15.4%) revealed discrepancy between the histology of the endoscopic biopsy and that of a resected specimen by EMR. The histology of a resected specimen by EMR revealed moderate differentiated adenocarcinoma, while that of endoscopic biopsy was a well differentiated adenocarcinoma. Gastric flat adenoma revealed 47.8% (11/23) of discrepancy.
CONCLUSIONS
The histologic discrepancy between the result of endoscopic biopsy and that of the resected specimen obtained by EMR was about 8% in EGC and 47.8% in gastric flat adenoma.

Keyword

Early gastric cancer; Gastric flat adenoma; EMR; Histologic discrepancy

MeSH Terms

Adenocarcinoma
Adenoma*
Biopsy*
Retrospective Studies
Stomach Neoplasms*