Korean J Dermatol.  2013 Oct;51(10):833-836.

A Localized Cutaneous Paecilomyces lilacinus Infection Treated with Voriconazole

Affiliations
  • 1Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. dylee@smc.samsung.co.kr

Abstract

Paecilomyces is a hyaline hyphomycete that exists worldwide. Paecilomyces lilacinus is associated most frequently with human infection. A 72-year-old male presented with a 1-month history of pruritic erythematous scaly plaque on his left shoulder. Tissue specimen from his cutaneous lesion showed granulomatous inflammation in the dermis and revealed fungal hyphae and spores within giant cells. The pathogen was identified as Paecilomyces lilacinus through fungus culture. Oral itraconazole was begun, but there was no improvement after 14 weeks. The lesions improved after treatment with oral voriconazole. We suggest that voriconazole as a promising useful therapeutic option in Paecilomyces lilacinus infection.

Keyword

Paecilomyces lilacinus; Voriconazole

MeSH Terms

Aged
Dermis
Fungi
Giant Cells
Humans
Hyalin
Hyphae
Inflammation
Itraconazole
Male
Mitosporic Fungi
Paecilomyces*
Pyrimidines
Shoulder
Spores
Triazoles
Itraconazole
Pyrimidines
Triazoles
Full Text Links
  • KJD
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr