J Korean Diabetes.  2011 Mar;12(1):60-63. 10.4093/jkd.2011.12.1.60.

A Case of Type 2 Diabetes Mellitus Improved after Surgical Treatment of Primary Hyperparathyroidism

• Jang YM
• Kim DL
• Lee EJ
• Song KH
• Kim SK

• KMID: 1851906
• DOI: http://doi.org/10.4093/jkd.2011.12.1.60

Abstract

Patients with primary hyperparathyroidism often exhibit insulin resistance and glucose intolerance. In previous studies, glucose intolerance was improved by parathyroidectomy in primary hyperparathyroidism. We report a case of type 2 diabetes mellitus that improved after resection of a parathyroid adenoma along with a review of the literature.

Keyword

Hyperparathyroidism; Diabetes; Glucose intolerance

MeSH Terms

Diabetes Mellitus, Type 2
Glucose Intolerance
Humans
Hyperparathyroidism
Hyperparathyroidism, Primary
Insulin Resistance
Parathyroid Neoplasms
Parathyroidectomy

Figure

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  Fig. 1. (A) 99mTc-setamibi scan showed nodular hot uptake in the left lower neck in early image (15 min). (B) In a delayed image (2 hr 30 min), accumulation of abnormal radioactivity in the left lower neck remained after washout of the thyroid gland activity.

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  Fig. 2. (A) Gross specimen of parathyroid adenoma (4.7 × 3.1 × 1.5 cm). (B) Microscopically (H&E, ×200), the adenoma is partly encapsulated and shows a solid sheet of tumor cells with mainly clear cytoplasm and round nuclei. Nuclear atypia is minimal and the mitotic activity is very low.

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