Korean J Hematol.  1998 Oct;33(3):460-465.

A Case of Relapsed Multiple Myeloma Presented as lntracranial Extramedullary Plasmacytoma

Affiliations
  • 1Department of Internal Medicine, Kyungpook National University, School of Medicine, Taegu, Korea.

Abstract

Intracranial plasmacytoma presented by extramedullary involvement of multiple myeloma is rarely reported. Neurologic complications by intracranial extramedullary plasmacytomas are cranial nerve palsy, visual disturbance, vertigo, nystagmus, headache, paralysis, mental change and etc. We experienced a case of relapsed multiple myeloma presented as intracranial extramedullary plasmacytoma. Brain magnetic resonance imaging(MRI) disclosed a large soft tissue mass involving the sphenoidal sinus and cavernous sinus which invaded optic chiasma, occulomotor nerve and pituitary gland. Relapsed multiple myeloma with intracranial extramedullary plasmacytoma was confined by trans-sphenoidal biopsy and urine electrophoresis. Neurologic complications of the patient was improved after cranial radiotherapy and systemic chemotherapy.

Keyword

Multiple myeloma; Intracranial extramedullary plasmacytoma

MeSH Terms

Biopsy
Brain
Cavernous Sinus
Cranial Nerve Diseases
Drug Therapy
Electrophoresis
Headache
Humans
Multiple Myeloma*
Optic Chiasm
Paralysis
Pituitary Gland
Plasmacytoma*
Radiotherapy
Vertigo
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