J Lipid Atheroscler.  2013 Dec;2(2):53-60. 10.12997/jla.2013.2.2.53.

Management of Hypertriglyceridemia for Prevention of Cardiovascular Diseases

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea. cjkim@cau.ac.kr

Abstract

Hypertriglyceridemia has been considered as a risk factor for cardiovascular diseases. However, triglyceride levels are influenced by many clinical and lipid risk factors. When triglyceride levels are adjusted by these variables, the effect of hypertriglyceridemia as a cardiovascular risk factor becomes minimal or negligible. Therefore, the association of hypertriglyceridemia with cardiovascular diseases is uncertain. The effect of triglyceride-lowering drugs on cardiovascular diseases is also unclear. These drugs failed to reduce cardiovascular events in relatively high risk patients with variable lipid profiles. However, subgroup analysis showed the cardioprotective effects in selected patients. It is clinically important whether a patient with hypertriglyceridemia should be treated with drug therapy or not. This paper discusses this issue based on limited data of published reports.

Keyword

Hypertriglyceridemia; Cardiovascular prevention

MeSH Terms

Cardiovascular Diseases*
Drug Therapy
Humans
Hypertriglyceridemia*
Risk Factors
Triglycerides

Cited by  2 articles

Quantitative Measurement of Effect of Short-term Life Style Modification on Lipid Profiles in Korean Patients with Hyperlipidemia
Young Kim, Moonki Jung, Chee Jeong Kim
J Lipid Atheroscler. 2016;5(1):79-86.    doi: 10.12997/jla.2016.5.1.79.

Effect of Long-term Fenofibrate Therapy on Serum Creatinine and Its Reversibility in Hypertriglyceridemic Patients with Hypertension
Gyu Tae Park, Moonki Jung, Young Kim, Iksung Cho, Hoyoun Won, Seung Yong Shin, Wang-Soo Lee, Kwang Je Lee, Sang-Wook Kim, Tae Ho Kim, Chee Jeong Kim
J Lipid Atheroscler. 2017;6(2):89-96.    doi: 10.12997/jla.2017.6.2.89.


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