J Korean Thyroid Assoc.
2013 Nov;6(2):96-100. 10.11106/jkta.2013.6.2.96.
Interactions between Immune Cells and Tumor Cells
- Affiliations
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- 1Department of Internal Medicine, Seoul National University College of Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea. swchomd@snu.ac.kr
- KMID: 1845379
- DOI: http://doi.org/10.11106/jkta.2013.6.2.96
Abstract
- Tumor microenvironment is defined as a heterogeneous complex composed of cancer cells, vascular endothelial cells, fibroblasts, and diverse immune cells. Cancer immunology is the study of interactions between the immune system and cancer cells which is applied to develop therapeutic strategies for human cancers. This review focused on tumor promoting myeloid derived cells such as tumor associated macrophages (TAM) and myeloid derived suppressor cells (MDSC) and their therapeutic applications.
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