Tuberc Respir Dis.  2012 Dec;73(6):331-335. 10.4046/trd.2012.73.6.331.

A Case of Invasive Thymoma with Endotracheal Polypoid Growth

• Hwang JT
• Kim MH
• Chang KJ
• Chang HJ
• Choi SJ
• Yuh YJ
• Kim JY
• Park HK

• KMID: 1842927
• DOI: http://doi.org/10.4046/trd.2012.73.6.331

Abstract

Thymomas are one of the most common neoplasms of the mediastinum derived from thymic epithelium. It is common that invasive thymoma invades the lung, pericardium, and great vessels. Airway compression by mass effect also occurs, but direct polypoid tumor growth into the airway is extremely rare. Only 20 cases of invasive thymoma with endobronchial polypoid growth have previously been reported globally. However, there is no case report of invasive thymoma with endotracheal growth. Herein, we report a rare case of invasive thymoma with endotracheal polypoid growth in a 28-year-old woman.

Keyword

Thymoma; Bronchoscopy

MeSH Terms

Bronchoscopy
Epithelium
Female
Humans
Lung
Mediastinum
Pericardium
Thymoma

Figure

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  Figure 1 Chest computed tomography showed about 3.3×2.4 cm sized homogenous enhancing mass in the right paratracheal area with tracheal stenosis and polypoid growth into the airway tract.

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  Figure 2 Bronchoscopic examination showed a polypoid tumor in the mid-trachea with obstruction of the tracheal lumen.

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  Figure 3 The tumor showed focal extension beyond tracheal cartilage to the tracheal subepithelial stroma (H&E stain, ×10).

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  Figure 4 Biopsy revealed proliferation of the epithelial cells with some mitotic figures. They are admixed a mild component of lymphocyte (H&E stain, ×400).

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  Figure 5 The tumor cells showed positive immunoreactivity for CD5 (×400).

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