Nucl Med Mol Imaging.  2009 Oct;43(5):505-507.

Sequential Change of Hypometabolic Metastasis from Non-small-cell Lung Cancer on Brain FDG-PET/CT

Affiliations
  • 1Department of Nuclear Medicine, Wonkwang University College of Medicine, Iksan, Korea. nmbach@wonkwang.ac.kr
  • 2Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Korea.
  • 3Department of Physical Medicine and Rehabilitation, Wonkwang University College of Medicine, Iksan, Korea.
  • 4Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.
  • 5Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Korea.

Abstract

A 60-year-old woman, who had non-small-cell lung cancer (NSCLC) in left lower lobe underwent brain F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for evaluation of cerebral metastasis. On follow-up FDG-PET/CT, only hypometaolic lesion was detected and progressed in right frontal lobe at 6 months and 10 months, later. Hypermetabolic metastasis was not detected even at last scan time of FDG-PET/CT. Brain MRI showed brain metastasis in right frontal lobe. As might be expected, the physician should take cerebral metastasis into consideration even though there is only hypometabolic change on subsequent FDG-PET/CT in patients with NSCLC.

Keyword

F-18 fluorodeoxyglucose; positron emission tomography/computed tomography; cerebral metastasis; non-small-cell lung cancer

MeSH Terms

Brain
Electrons
Female
Follow-Up Studies
Frontal Lobe
Humans
Lung
Lung Neoplasms
Middle Aged
Neoplasm Metastasis
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