Korean J Med.  2013 Mar;84(3):325-332. 10.3904/kjm.2013.84.3.325.

Hepatocellular Adenoma and Focal Nodular Hyperplasia

  • 1Department of Internal Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea. drwon1@snu.ac.kr


Recent advances in imaging technologies have offered us a great chance to detect a variety of focal liver lesions. Accordingly, it is of paramount importance to determine whether these focal liver lesions are malignant or nonmalignant. Some benign hepatic tumors mimicking hepatocellular carcinoma typically develop from either regenerative or dysplastic/neoplastic processes. The most common benign hepatic solid tumors that are not of vascular origin include focal nodular hyperplasia and hepatocellular adenoma. A majority of patients with benign hepatic tumors are often asymptomatic and require no specific treatment. However, surgical resection may be infrequently needed for cases with clinical symptoms or malignant potential. This review will touch on the epidemiology, pathogenesis, clinical features, diagnosis, and management of focal nodular hyperplasia and hepatocellular adenoma.


Benign hepatic tumor; Hepatocellular adenoma; Focal nodular hyperplasia

MeSH Terms

Adenoma, Liver Cell
Carcinoma, Hepatocellular
Focal Nodular Hyperplasia
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