Korean J Gastrointest Endosc.  2011 Jan;42(1):28-32.

A Case of Synchronous Colorectal Adenocarcinoma with Anal Squamous Cell Carcinoma

• Jung BY
• Lee SH
• Lee CK
• Park ES
• Chung IK
• Kim SJ
• Baek MJ
• Lee JH

Abstract

Synchronous anal squamous cell carcinoma with colorectal adenocarcinoma is a very rare and interesting disease entity because these neoplasms are essentially different from each other in terms of their anatomical locations, clinical behaviors, histopathological characteristics and treatment. To date, there have been very few case reports regarding the concurrent occurrence of these two distinct neoplasms. Nonetheless, it is recommended that patients with squamous cell carcinoma of the anus and who are older than 50 years should undergo colonoscopy in order to rule out a synchronous colorectal neoplasm. We recently encountered a 72-year-old woman who presented with synchronous squamous cell carcinoma of the anal canal and adenocarcinoma of the rectosigmoid junction. The patient underwent curative surgical resection for the colorectal adenocarcinoma and chemoradiotherapy for the concurrent anal squamous cell carcinoma. We describe here our clinical experience with this unusual case and we also conduct a short review of relevant literature.

Keyword

Synchronous cancer; Colon neoplasms; Anal neoplasm; Adenocarcinoma; Squamous cell carcinoma

MeSH Terms

Adenocarcinoma
Aged
Anal Canal
Anus Neoplasms
Carcinoma, Squamous Cell
Chemoradiotherapy
Colonic Neoplasms
Colonoscopy
Colorectal Neoplasms
Female
Humans