Korean Circ J.  2010 Oct;40(10):527-529. 10.4070/kcj.2010.40.10.527.

Successful Percutaneous Coronary Intervention for Acute Coronary Syndrome in a Patient With Severe Hemophilia A

Affiliations
  • 1Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea. jo1216@chollian.net
  • 2Division of Cardiology, Department of Internal Medicine, Ulsan Hospital, Ulsan, Korea.
  • 3Division of Cardiology, Department of Internal Medicine, Changwon Fatima Hospital, Changwon, Korea.

Abstract

Patients with hemophilia generally have a reduced frequency of coronary artery disease compared to the general population. As advances in the management of hemophilia have increased their life expectancy, the prevalence of coronary artery disease also has increased. However, there are no standard treatment guidelines for coronary artery disease in patients with hemophilia, especially in the field of coronary intervention. We report the case of a patient with severe hemophilia A who presented with acute coronary syndrome and was successfully treated with percutaneous coronary intervention.

Keyword

Hemophilia A; Percutaneous transluminal angioplasty; Acute Coronary Syndrome

MeSH Terms

Acute Coronary Syndrome
Angioplasty
Coronary Artery Disease
Hemophilia A
Humans
Life Expectancy
Percutaneous Coronary Intervention
Prevalence

Figure

  • Fig. 1 Initial coronary angiography. Coronary angiography reveals focal luminal narrowing at the proximal and mid segments of the left anterior descending artery (A). Bare-metal stent (Vision®, Abbott Inc, Santa Clara, CA, USA) was successfully implanted at the proximal lesion (B).

  • Fig. 2 Follow-up coronary angiography 10 months after the initial procedure. Coronary angiography showed 70% in-stent restenosis at the proximal left anterior descending artery (arrows). However, the patient was asymptomatic but managed with medical therapy.


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