Korean Circ J.
2009 Mar;39(3):87-92. 10.4070/kcj.2009.39.3.87.
Is Stem Cell-Based Therapy Going on or Out for Cardiac Disease?
- Affiliations
-
- 1Division of Cardiology, Department of Internal Medicine, Kwandong University College of Medicine, Goyang, Korea. cardio101@daum.net
- 2Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, USA.
- KMID: 1825963
- DOI: http://doi.org/10.4070/kcj.2009.39.3.87
Abstract
- Acute myocardial infarction and subsequent heart failure are leading causes of death worldwide. Stem cell-based therapies have improved cardiac function in recent clinical trials, but cardiomyocyte regeneration has not been demonstrated in human hearts. Angiogenesis and restoration of cardiac perfusion have been successfully performed using bone marrow derived stem cells and other adult stem cells. Resident cardiac stem cells are known to differentiate into multiple heart cell types, including cardiomyocytes. Furthermore, induced pluripotent stem cells are a focus of research due to the great potential for customized stem cell therapy.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Current Concepts in Stem Cell Therapy for Cardiovascular Diseases: What We Know and Don't Know
- The Role of Large Animal Studies in Cardiac Regenerative Therapy Concise Review of Translational Stem Cell Research
- Cell Biological Characteristics of Adult Stem Cells
- Current Status of G-CSF Based Stem Cell Therapy for Patients with Myocardial Infarction
- Clinical application of stem cell in cardiovascular diseases
