J Periodontal Implant Sci.  2014 Dec;44(6):280-287. 10.5051/jpis.2014.44.6.280.

Effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial

Affiliations
  • 1Department of Periodontology, Ewha Womans University Mokdong Hospital, Seoul, Korea. ekpang@ewha.ac.kr
  • 2Department of Oral and Maxillofacial Surgery, Ewha Womans University Medical Center, Seoul, Korea.
  • 3Department of Periodontology, Ewha Womans University Graduate School of Medicine, Seoul, Korea.

Abstract

PURPOSE
The purpose of this randomized single-blind controlled trial was to elucidate the clinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling and root planing (SRP) in patients with chronic periodontitis.
METHODS
The study was conducted from December 2013 to May 2014 at Ewha Womans University Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderate chronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio: SRP+PT and SRP (control) groups. All participants underwent full-mouth SRP. PT was performed thrice a day for a month by using electric toothbrushes with embedded light-emitting diodes. Plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing were assessed before (baseline) and four weeks after (follow-up) the treatment. Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia, Fusobacterium nucleatum, Parvimonas micra, Campylobacter rectus, Eikenella corrodens, Streptococcus mutans, and Streptococcus sobrinus levels were detected by a real-time polymerase chain reaction at the same points in time.
RESULTS
The clinical parameters improved in both the groups. At the follow-up assessment, PPD was significantly decreased in the SRP+PT group (P=0.00). Further, PPD and CAL showed significantly greater changes in the SRP+PT group than in the SRP group (PPD, P=0.03; CAL, P=0.04). P. gingivalis and T. forsythia levels decreased in this group, but no significant intergroup differences were noted.
CONCLUSIONS
Adjunctive PT seems to have clinical benefits, but evidence of its antimicrobial effects is not sufficient. Long-term studies are necessary to develop the most effective PT protocol and compare the effectiveness of PT with and without exogenous photosensitizers.

Keyword

Dental scaling; Periodontal index; Periodontitis; Photochemotherapy; Photosensitizing agents

MeSH Terms

Aggregatibacter actinomycetemcomitans
Campylobacter rectus
Chronic Periodontitis*
Dental Scaling
Eikenella corrodens
Female
Follow-Up Studies
Forsythia
Fusobacterium nucleatum
Hemorrhage
Humans
Korea
Periodontal Index
Periodontitis
Photochemotherapy
Photosensitizing Agents
Phototherapy*
Porphyromonas gingivalis
Prevotella intermedia
Real-Time Polymerase Chain Reaction
Root Planing
Seoul
Streptococcus mutans
Streptococcus sobrinus
Treponema denticola
Photosensitizing Agents

Figure

  • Figure 1 Study flowchart showing the participants enrolled in this study.

  • Figure 2 Mean bacterial amounts obtained from subgingival biofilm at baseline (A) and 4 weeks (B) posttreatment (log10±SEM). SEM: standard error of mean, Aa: Aggregatibacter actinomycetemcomitans, Pg: Porphyromonas gingivalis, Tf: Tannerella forsythia, Td: Treponema denticola, Pi: Prevotella intermedia, Fn: Fusobacterium nucleatum, Pm: Parvimonas micra, Cr: Campylobacter rectus, Ec: Eikenella corrodens, Sm: Streptococcus mutans, Ss: Streptococcus sobrinus.


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