J Korean Surg Soc.  2012 Aug;83(2):107-110. 10.4174/jkss.2012.83.2.107.

Giant sized epidermal inclusion cyst of the breast initially mimicking a large fibroadenoma or phyllodes tumor

• Lee YA
• Park SG

• KMID: 1820096
• DOI: http://doi.org/10.4174/jkss.2012.83.2.107

Abstract

Epidermal inclusion cysts are formed by inclusion of keratinizing squamous epithelium within the dermis, resulting in a cyst filled with lamellated keratin. These benign cysts are usually very small and intradermal subcutaneous lesions. They can occur anywhere in the body although they are more common on the face, trunk, neck, extremities and scalp. Only a few cases of epidermal cysts of the breast have been reported in the literature. An epidermal inclusion cyst of the breast can result in several problems, even if the size is unusual. We encountered a case of a giant sized epidermal inclusion cyst of the breast initially mimicking a large fibroadenoma or phyllodes tumor.

Keyword

Epidermal cyst; Breast neoplasms

MeSH Terms

Breast
Breast Neoplasms
Dermis
Epidermal Cyst
Epithelium
Extremities
Fibroadenoma
Keratins
Neck
Phyllodes Tumor
Scalp
Keratins

Figure

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  Fig. 1 Mammography showed a round, dense, smoothly outlined mass measuring 7 × 6 cm. LCC, left craniocaudal; LMLO, left mediolateral oblique.

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  Fig. 2 Breast sonography showed solid, hypoechoic with heterogeneous internal echoes and well demarcated border.

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  Fig. 3 (A, B) Epidermal inclusion cyst lined by cornified epithelium with distinct granular layer containing lamellated keratin material (H&E, ×100). (C) Cholesterol cleft surrounded by giant cell, histiocytes suggesting microruptured cyst (H&E, ×200).

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