J Korean Child Neurol Soc.
2004 Nov;12(2):241-246.
A Case of Familial Moyamoya Disease: A Case in Brother and Sister
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Soonchunhyang University, Seoul, Korea. essuh@hosp.sch.ac.kr
- 2Department of Neurosurgery, College of Medicine, Soonchunhyang University, Seoul, Korea.
Abstract
- Moyamoya disease is a progressive and occlusive disorder of the cerebral vasculature with particular involvements of the circle of Willis and the arteries that feed it. It occurs commonly in Japan and Korea, but less frequently in the Western countries. The etiology of moyamoya disease is still unclear, but frequent familial occurrence suggests that some genetic factors may be important in its etiology. Approximately 7-10% of moyamoya disease are familial. We experienced 2 siblings with moyamoya disease, and report the case with a review of previously published cases of moyamoya disease within a family.
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