Cancer Res Treat.  2004 Feb;36(1):13-18.

Recent Advances in Management of Laryngeal Cancer

Affiliations
  • 1Department of Otorhinolaryngology and Head and Neck Surgery, Korea Cancer Center Hospital, Seoul, Korea.

Abstract

Laryngeal cancers account for approximately 1.5% (1~2%) of the total cancers in Korea, and 30% of all head and neck cancers, not including thyroid cancer. Early laryngeal cancer is treated by operation, including transoral laser excision or radiotherapy. Advanced laryngeal cancer has been treated with mutilating operations, such as a total laryngectomy. However, a laryngeal preserving approach, which can improve the quality of life, has recently been tried with advanced laryngeal cancer.

Keyword

Laryngeal cancer; Laser surgery; Neoadjuvant chemotherapy

MeSH Terms

Head
Korea
Laryngeal Neoplasms*
Laryngectomy
Laser Therapy
Neck
Quality of Life
Radiotherapy
Thyroid Neoplasms

Figure

  • Fig. 1 Incidence of laryngeal and lung cancers in Korea. (1993~2000, Statistics of Cancer Registration in Korea, National Cancer Center).

  • Fig. 2 Transoral laser surgery (left: preoperation, right: postoperation).


Reference

1. Absolon KB. Theodore Billroth in Vienna 1867~1880. Aust N Z J Surg. 1977; 47:837–844. PMID: 348184.
2. Brunschwig A. Panlaryngectomy for advanced carcinoma of the larynx. Surg Gynecol Obstet. 1943; 76:390–394.
3. Cragle SP, Brandenburg JH. Laser cordectomy or radiotherapy: Cure rates, communication, and cost. Otolaryngol Head Neck Surg. 1993; 108:648–654. PMID: 8516002.
Article
4. Foote RL, Buskirk SJ, Grado GL, Bonner JA. Has radiotherapy become too expensive to be considered a treatment option for early glottic cancer? Head Neck. 1997; 19:692–700. PMID: 9406748.
Article
5. Rosier JF, Gregoire V, Counoy H, Octave-Prignot M, Rombaut P, Scaliet P, Vanderlinden F, Hamoir M. Comparison of external radiotherapy, laser microsurgery and partial laryngectomy for the treatment of T1N0M0 glottic carcinomas: a retrospective evaluation. Radiother Oncol. 1998; 48:175–183. PMID: 9783889.
Article
6. Epstein BE, Lee DJ, Kashima H, Johns ME. Stage T1 glottic carcinoma: results of radiation therapy or laser excision. Radiology. 1990; 175:567–570. PMID: 2326483.
Article
7. Luscher MS, Pedersen U, Johansen LV. Treatment outcome after laser excision of early glottic squamous cell carcinoma (A literature survey). Acta Oncol. 2001; 40:796–800. PMID: 11859977.
8. Motta G, Esposito E, Cassiano B, Motta S. T1-T2-T3 glottic tumors: fifteen years' experience with CO2 laser. Acta Otolaryngol Suppl. 1997; (Suppl 527):155–159. PMID: 9197509.
9. Krespi YP, Meltzer CJ. Laser surgery for vocal cord carcinoma involving the anterior commissure. Ann Otol Rhinol Laryngol. 1989; 98:105–109. PMID: 2916820.
Article
10. Wolfensberger M, Dort JC. Endoscopic laser surgery for early glottic carcinoma: a clinical and experimental study. Laryngoscope. 1990; 100:1100–1105. PMID: 2215043.
Article
11. Beitler JJ, Johnson JT. Transoral laser excision for early glottic cancer. Int J Radiat Oncol Biol Phys. 2003; 56:1063–1066. PMID: 12829142.
Article
12. Krajina ZF, Kosokovic S, Vecerina S. Laryngeal reconstruction with sternohyoid fascia in partial laryngectomy. J Laryngol Otol. 1979; 93:1181–1186. PMID: 528818.
Article
13. Hall FT, O'Brien CJ, Clifford AR, McNeil EB, Bron L, Jackson MA. Clinical outcome following total laryngectomy for cancer. ANZ J Surg. 2003; 73:300–305. PMID: 12752286.
Article
14. Schwaab G, Kolb F, Julieron M, Janot F, Le Ridant AM, Mamelle G, Marandas P, Koka VN, Luboinski B. Subtotal laryngectomy with cricohyoidopexy as first treatment procedure for supraglottic carcinoma: Institut Gustave-Roussy experince (146 cases, 1974-1997). Eur Arch Otorhinolaryngol. 2001; 258:246–249. PMID: 11548904.
15. Laccourreye O, Weinstein G, Naudo P, Cauchois R, Laccourreye H, Brasnu D. Supracricoid partial laryngectomy after failed laryngeal radiation therapy. Laryngoscope. 1996; 106:495–498. PMID: 8614228.
Article
16. Wolf GT, Hong WK. Induction chemotherapy as part of a new treatment strategy to preserve the larynx in advanced laryngeal cancer. Head and Neck Cancer. 1993; 3:27–35.
17. Richard JM, Sancho-Garnier H, Pessey JJ, Luboinski B, Lefebvre JL, Dehesdin D, Stranboni-Luboinski M, Hill C. Randomized trial of induction chemotherapy in larynx carcinoma. Oral Oncol. 1998; 34:224. PMID: 9692058.
Article
18. Lefebvre JL, Chevalier D, Luboinski B, Kirkpatrick A, Collette L, Sahmoud T. Larynx preservation in pyriform sinus cancer: preliminary results of a European Organization for Research and Treatment of Cancer phase III study. J Natl Cancer Inst. 1996; 13:890. PMID: 8656441.
19. Lefebvre JL, Wolf G, Luboinski B, Pessey JJ. Meta-analysis of preservation using neoadjuvant chemotherapy (CT) in laryngeal and hypopharyngeal carcinoma. Proc Am Soc Clin Oncol. 1998; 17:1473.
20. Wylie JP, Sen M, Swindell R, Sykes AJ, Farrington WT, Slevin NJ. Definitive radiotherapy for 114 cases of T3N0 glottic carcinoma: influence of dose- volume parameters on outcome. Radiother Oncol. 1999; 53:15. PMID: 10624848.
21. Overgaard J, Hansen HS, Overgaard M, Bastholt L, Berthelsen A, Specht L, Lindelov B, Jorgensen K. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol. 1998; 46:135–146. PMID: 9510041.
Article
22. Merlano M, Vitale V, Rosso R, Benasso M, Corvo R, Cavallari M, Sanguineti G, Bacigalupo A, Badellino F, Margarino G. Treatment of advanced squamous-cell carcinoma of the head and neck with alternating chemotherapy and radiotherapy. N Engl J Med. 1992; 327:1115. PMID: 1302472.
Article
23. Brizel DM, Albers ME, Fisher SR, Scher RL, Richtsmeier WJ, Hars V, George SL, Huang AT, Prosnitz LR. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998; 338:1798. PMID: 9632446.
Article
Full Text Links
  • CRT
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr