Clin Endosc.  2015 Mar;48(2):142-146. 10.5946/ce.2015.48.2.142.

Light-Emitting Diode-Assisted Narrow Band Imaging Video Endoscopy System in Head and Neck Cancer

• Chang HJ
• Wang WH
• Chang YL
• Jeng TR
• Wu CT
• Angot L
• Lee CH
• Wang PC

• KMID: 1801205
• DOI: http://doi.org/10.5946/ce.2015.48.2.142

Abstract

BACKGROUND/AIMS
To validate the effectiveness of a newly developed light-emitting diode (LED)-narrow band imaging (NBI) system for detecting early malignant tumors in the oral cavity.
METHODS
Six men (mean age, 51.5 years) with early oral mucosa lesions were screened using both the conventional white light and LED-NBI systems.
RESULTS
Small elevated or ulcerative lesions were found under the white light view, and typical scattered brown spots were identified after shifting to the LED-NBI view for all six patients. Histopathological examination confirmed squamous cell carcinoma. The clinical stage was early malignant lesions (T1), and the patients underwent wide excision for primary cancer. This is the pilot study documenting the utility of a new LED-NBI system as an adjunctive technique to detect early oral cancer using the diagnostic criterion of the presence of typical scattered brown spots in six high-risk patients.
CONCLUSIONS
Although large-scale screening programs should be established to further verify the accuracy of this technology, its lower power consumption, lower heat emission, and higher luminous efficiency appear promising for future clinical applications.

Keyword

Light-emitting diode; Narrow band imaging; Endoscopy; Screening; Mouth neoplasms

MeSH Terms

Carcinoma, Squamous Cell
Endoscopy*
Head and Neck Neoplasms*
Hot Temperature
Humans
Male
Mass Screening
Mouth
Mouth Mucosa
Mouth Neoplasms
Narrow Band Imaging*
Pilot Projects
Ulcer

Figure

• 

  Fig. 1 Case 6, (A) left buccal mucosa lesion (1.8×1.7 cm2). (B) The narrow band imaging examination uncovered a well-demarcated brownish area with scattered brown spots. Histopathology revealed squamous cell carcinoma, moderately differentiated.

• 

  Fig. 2 (A) Light-emitting diode (LED)-narrow band imaging light source PR650, cursors for 0% to 100% white, green/blue light mix. (B) Left ⇨: white LED chip; right ⇦: green/blue LED chips. (C) Close-up view: green/blue LED chips.

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