Brain Neurorehabil.
2014 Sep;7(2):147-150. 10.12786/bn.2014.7.2.147.
Trial of Metoclopramide on Oro-facial Dyskinesia Following Traumatic Brain Injury: A Case Report
- Affiliations
-
- 1Department of Rehabilitation Medicine, Severance Hospital, Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea.
- 2Department of Rehabilitation Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea. rekhs@nhimc.or.kr
- KMID: 1797650
- DOI: http://doi.org/10.12786/bn.2014.7.2.147
Abstract
- Oro-facial dyskinesia is characterized by involuntary repetitive movements of the tongue, lip, or jaw, which is known to be derived by variable causes. Pre- and post-synaptic dopamine receptor abnormalities by degenerative changes in the brain seem to be the key pathophysiology, but the exact mechanism still remained to be unknown. Metoclopramide can pass the blood-brain barrier, which is known for a selective presynaptic autoregulating dopamine D2 receptor antagonist in the brain, and is usually prescribed for dyspepsia, nausea and vomiting. In particular, it was also reported to improve the symptoms of diurnal bruxism after brain injury. With reviewing some of literatures, we present a case of 27 year old man with traumatic brain injury who showed improvement of oro-facial dyskinesia after taking oral metoclopramide.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Seven Cases of Successful Remission after Trial of Metoclopramide on Orofacial Dyskinesia of Stroke Patients: a Case Series
- Four cases of Senile Oro-facial Dyskinesia and Discussion on the pathophysiology
- Trial of Oral Metoclopramide on Diurnal Bruxism of Brain Injury
- Delayed Bilateral Facial Nerve Palsy Manifesting 3 Months after Traumatic Brain Injury: A Case Report
- The Relationship of the Facial Injury Location and the Traumatic Brain Hemorrhage
