J Korean Med Sci.  2014 Sep;29(9):1271-1277. 10.3346/jkms.2014.29.9.1271.

A Prospective Korean Multicenter Study for Infectious Complications in Patients Undergoing Prostate Surgery: Risk Factors and Efficacy of Antibiotic Prophylaxis

• Hwang EC
• Jung SI
• Kwon DD
• Lee G
• Bae JH
• Na YG
• Min SK
• Son H
• Lee SJ
• Chung JM
• Chung H
• Cho IR
• Kim YH
• Kim TH
• Chang IH

• KMID: 1794607
• DOI: http://doi.org/10.3346/jkms.2014.29.9.1271

Abstract

This multicenter study was undertaken to determine the efficacy of antibiotic prophylaxis and identify the risk factors for infectious complications after prostate surgery in Korean patients. A total of 424 patients who underwent surgery of the prostate were reviewed. All patients underwent urinalysis and urine culture preoperatively and postoperatively. Efficacy of antibiotic prophylaxis and risk factors for infectious complications were investigated. Infectious complications were observed in 34.9% of all patients. Factors independently associated with infectious complications were diabetes mellitus (adjusted OR, 1.99; 95% CI, 1.09-3.65, P=0.025) and operation time (adjusted OR, 1.08; 95% CI, 1.03-1.13, P=0.004). Clinicians should be aware of the high risk of infectious complications in patients with diabetes and those who undergo a prolonged operation time. Neither the type nor duration of prophylactic antibiotics resulted in differences in infectious complications.

Keyword

Urinary Tract Infections; Transurethral Resection of Prostate; Risk Factors

MeSH Terms

Aged
Anti-Bacterial Agents/pharmacology/therapeutic use
Antibiotic Prophylaxis
Diabetes Mellitus, Type 2/complications
Drug Resistance, Bacterial/drug effects
Enterococcus/drug effects/isolation & purification
Escherichia coli/isolation & purification
Humans
Klebsiella pneumoniae/drug effects/isolation & purification
Male
Middle Aged
Odds Ratio
Postoperative Complications/microbiology/prevention & control
Prospective Studies
Prostatic Neoplasms/complications/*surgery
Quinolones/pharmacology
Risk Factors
Time Factors
Transurethral Resection of Prostate
Urinalysis
Urinary Tract Infections/microbiology
Anti-Bacterial Agents
Quinolones

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