Korean J Leg Med.  2015 May;39(2):36-40. 10.7580/kjlm.2015.39.2.36.

Homicidal Paraquat Poisoning in Exhumed Case

Affiliations
  • 1Forensic Medical Center, National Forensic Service, Wonju, Korea. zzeva@korea.kr
  • 2Narcotics, Forensic Toxicology & Chemistry Division, Seoul Institute, National Forensic Service, Seoul, Korea.

Abstract

Paraquat is a nonselective herbicide, but its lethal and toxic effects are well known. Although its chemical additives have an unpleasant taste, this can be shrouded in spicy foods or drinks with strong tastes, and some symptoms and signs of paraquat poisoning can be mistaken as natural disease. For this reason, it is not easy to consider the possibility of homicidal paraquat poisoning for a clinician or even for a forensic pathologist. We present a case of homicidal poisoning by paraquat with significant forensic findings from postmortem examination and with a review of relevant literature.

Keyword

Paraquat; Homicide; Poisoning; Autopsy; Forensic pathology

MeSH Terms

Autopsy
Forensic Pathology
Homicide
Paraquat*
Poisoning*
Paraquat

Reference

1. Tsokos M. Forensic pathologic reviews. Vol. 4. Totowa: Humana Press Inc.;2006. p. 261–327.
2. Paraquat Information Center. Safety to humans [Internet]. Paraquat Information Center; [cited 2015 May 1]. Available from:. http://paraquat.com/safety/safety-to-humans.
3. So BH, Lee MJ, Kim H, et al. 2008 Database of Korean toxic exposures: a preliminary study. J Korean Soc Clin Toxicol. 2010; 8:51–60.
4. Kim YS, Lee H, Jung YK, et al. Paraquat poisoning by injection: 3 autopsy cases. Korean J Leg Med. 2000; 24:87–91.
5. Houze P, Baud FJ, Mouy R, et al. Toxicokinetics of paraquat in humans. Hum Exp Toxicol. 1990; 9:5–12.
Article
6. Suntres ZE. Role of antioxidants in paraquat toxicity. Toxicology. 2002; 180:65–77.
Article
7. Wilks MF, Tomenson JA, Fernando R, et al. Formulation changes and time trends in outcome following paraquat ingestion in Sri Lanka. Clin Toxicol (Phila). 2011; 49:21–8.
Article
8. Kim JH, Gil HW, Yang JO, et al. Serum uric acid level as a marker for mortality and acute kidney injury in patients with acute paraquat intoxication. Nephrol Dial Transplant. 2011; 26:1846–52.
Article
9. Gawarammana IB, Buckley NA. Medical management of paraquat ingestion. Br J Clin Pharmacol. 2011; 72:745–57.
Article
10. Dinis-Oliveira RJ, de Pinho PG, Santos L, et al. Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive therapies in paraquat human intoxications. PLoS One. 2009; 4:e7149.
Article
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