Yonsei Med J.  2008 Aug;49(4):662-665. 10.3349/ymj.2008.49.4.662.

Delayed Epithelial Ingrowth Caused by Viral Conjunctivitis after LASIK

Affiliations
  • 1Department of Ophthalmology School of Medicine, Ewha Womans University, Seoul, Korea. eungkkim@yuhs.ac
  • 2Institute of Vision Research, Department of Ophthalmology, BK21 Project Team of Nanobiomaterials for Cell-based Implants, Yonsei University, Seoul, Korea.

Abstract

To report a patient who presented with epithelial ingrowth caused by viral keratoconjunctivitis 3 months after LASIK surgery. A 41-year-old man presented with decreased visual acuity in the right eye, which had developed about 3 weeks before. He had undergone LASIK surgery 3 months prior without complications. Two months after the surgery, he was treated for viral conjunctivitis. During the treatment period, filamentary keratitis developed, and a therapeutic bandage contact lens was applied for 2 weeks. Upon presentation, examination revealed a corrected visual acuity of 20/100 and irregular epithelial sheets under the edematous flap. The flap was lifted, and the in-grown epithelium was removed. The flap was repositioned with double continuous 10-0 nylon sutures. Post-operatively, the patient developed a mild diffuse lamellar keratitis that resolved rapidly with topical corticosteroid treatment. At 2 months, the corrected visual acuity was 20/20 without interface opacities. As the patient showed no complications prior to viral conjunctivitis, we suspect that the viral infection caused edema of the corneal flap, which caused epithelial ingrowth under the flap. Patients who have viral conjunctivitis after LASIK surgery should be examined carefully and managed with consideration of flap complications.

Keyword

Epithelial ingrowth; laser in situ keratomileusis; viral conjunctivitis

MeSH Terms

Adult
Cell Proliferation
Conjunctivitis, Viral/*etiology/*pathology
Epithelial Cells/*pathology
Humans
Keratomileusis, Laser In Situ/*adverse effects
Male

Figure

  • Fig. 1 On initial examination in our clinic, there were irregular opacities underneath the flap. (A) The flap is edematous and seems to be detached from the remaining stromal bed. (B) On fluorescein staining, an epithelial defect involving the temporal one-third of the anterior flap surface was noted.

  • Fig. 2 After removal of the epithelial ingrowth, moderate flap edema and hazy interface opacities were observed. Double continuous 10 - 0 nylon sutures were made to prevent the recurrence of epithelial ingrowth.

  • Fig. 3 Corneal finding two months after the removal of epithelial ingrowth and corneal suturing. Recurrence of any epithelial ingrowth was not noted one month after removal of sutures.


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