Korean J Gastroenterol.  2013 Oct;62(4):243-247. 10.4166/kjg.2013.62.4.243.

A Case of Crohn's Disease Accompanied by Peutz-Jeghers Syndrome

  • 1Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. ismkim@kyuh.co.kr


Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by multiple gastrointestinal hamartomatous polyps and mucocutaneous pigmentation. Peutz-Jeghers syndrome has an incidence of approximately 1 in 25,000 to 300,000 births. Crohn's disease is a chronic inflammatory bowel disease that typically manifests as regional enteritis with its incidence ranging from 3.1 to 14.6 cases per 100,000 person-years in North America. Herein, we report a case of a 30-year-old male patient who had both Peutz-Jeghers syndrome and Crohn's disease. We believe that this is the first case in Korea and the second report in the English literatures on Peutz-Jeghers syndrome coincidentally accompanied by Crohn's disease.


Peutz-Jeghers syndrome; Crohn disease; Hamartomatous polyp; Inflammatory bowel diseases
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