Korean J Parasitol.
2012 Dec;50(4):339-343.
An Outbreak of Trichinosis with Molecular Identification of Trichinella sp. in Vietnam
- Affiliations
-
- 1Department of Parasitology, Hanoi Medical University, Vietnam. ngvdeyhn@gmail.com
- 2National Hospital of Tropical Diseases, Hanoi, Vietnam.
- 3National Centre for Veterinary Diagnosis, Hanoi, Vietnam.
- 4Bach Mai Hospital, Hanoi, Vietnam.
- 5Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Abstract
- The 5th outbreak of trichinosis occurred in a mountainous area of North Vietnam in 2012, involving 24 patients among 27 people who consumed raw pork together. Six of these patients visited several hospitals in Hanoi for treatment. Similar clinical symptoms appeared in these patients within 5-8 days after eating infected raw pork, which consisted of fever, muscle pain, difficult moving, edema, difficult swallowing, and difficult breathing. ELISA revealed all (6/6) positive reactions against Trichinella spiralis antigen and all cases showed positive biopsy results for Trichinella sp. larvae in the muscle. The larvae detected in the patients were identified as T. spiralis (Vietnamese strain) by the molecular analysis of the mitochondrial cytochrome c oxidase subunit III (cox3) gene.
Keyword
MeSH Terms
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Adult
Animals
Antigens, Helminth/analysis/immunology
*Disease Outbreaks
Electron Transport Complex IV/genetics
Enzyme-Linked Immunosorbent Assay
Female
Humans
Larva
Male
Meat/*parasitology
Mitochondria/genetics
Muscles/parasitology/pathology
Swine
Trichinella spiralis/genetics/immunology/*isolation & purification
Trichinellosis/*epidemiology/parasitology/pathology
Vietnam/epidemiology
Antigens, Helminth
Electron Transport Complex IV
